产品货号：
Z33354
中文名称：
Bcl-XL/BCL2L1抗体
英文名称：
Anti-Bcl-XL/BCL2L1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Bcl-XL/BCL2L1 Antibody |
| 指标别名 | Apoptosis regulator Bcl X;BCL2L1;Bcl-XL |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP |
| 基因名称 | BCL2L1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Bcl-XL |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Bcl-2-like protein 1 is a protein that in humans is encoded by the BCL2L1 gene.The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The proteins encoded by this gene are located at the outer mitochondrial membrane,and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening.VDAC regulates mitochondrial membrane potential,and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria,both of which are the potent inducers of cell apoptosis.Alternative splicing results in multiple transcript variants encoding two different isoforms.The longer isoform (Bcl-xL) acts as an apoptotic inhibitor and the shorter form (Bcl-xS) acts as an apoptotic activator. |
| Uniprot ID | Q07817 |
| 基因名全称 | Bcl-2-like protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 |
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